منابع مشابه
Mining immune epitopes in the inner ear.
Etiologies for many inner ear disorders, including autoimmune inner ear disease, sudden sensorineural hearing loss, and Meniere's disease, remain unknown. Indirect evidence suggests an immune-mediated process involving an allergic or autoimmune mechanism. We examined whether known immunogenic proteins share sequence similarity with inner ear proteins, which may lead to cross-reactivity and detr...
متن کاملAutoimmune Inner Ear Disease- A Clinical Viewpoint
Recent developments in medicine have given us a better insight into a group of disorders known as autoimmune diseases. In particular, advances have occurred in our understanding of the Autoimmune Inner Ear Disease (AIED). In this article, the authors review the different postulated theories in the pathogenesis of this disease. The clinical presentation, the available para-clinical diagnostic to...
متن کاملElectroporation-mediated gene transfer to the developing mouse inner ear.
The mammalian inner ear forms from a thickened patch of head ectoderm called the otic placode. The placodal ectoderm invaginates to form a cup whose edges cinch together to establish a fluid-filled sac called the otic vesicle or otocyst. The progenitor cells lining the otocyst lumen will give rise to sensory and non-sensory cells of the inner ear. These formative stages of inner ear development...
متن کاملInside the inner ear
There are dozens of different myosin isozymes, though it's not clear why cells require such a diversity. These images of fluorescently-labelled hair cells from the inner ears of frog, guinea pig and mouse show the localization of actin (red at top left and bottom right) and of four different forms of myosin (green, except at bottom left, where myosin VI is labelled in red). Hair cells are the r...
متن کاملManagement of Immune-Mediated Paraneoplastic Neurological Disorders
Paraneoplastic neurological syndromes (PNS) are immune-mediated paraneoplastic disorders of the nervous system caused by tumor-induced disturbance of immune tolerance to neuronal antigens. Tumors expressing neuronal proteins, either intracellularly or on cell membranes, are most relevant (▶Table 1). The detection of antineuronal antibodies (Abs) confirms the diagnosis of PNS in patients present...
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ژورنال
عنوان ژورنال: Practica Oto-Rhino-Laryngologica
سال: 1992
ISSN: 1884-4545,0032-6313
DOI: 10.5631/jibirin.85.315